The Seg-Flow® 4800 Automated On-line Sampling System provides multiple bioprocess monitoring and control solutions for improving process performance. The Seg-Flow 4800 system’s patented Segmented On-line Sampling™ technology allows rapid and accurate sampling for 8 vessels and sample delivery to 4 analyzers and/or fraction collectors. Several feed control options are available with the Seg-Flow 4800 system, which can control 2 pumps per vessel. Existing off-line and at-line analytics are seamlessly integrated into a multi-functional on-line PAT tool through the Seg-Flow 4800 system’s communication interface and FlowWeb™ control software. The FlowWeb software simultaneously acquires all integrated instrument data and can export the data to any OPC-enabled SCADA system for enhanced process monitoring and control.