Nova Biomedical BioProfile FLEX2 Integration
The Flownamics Seg-Flow® PS Fully Automated Sampling System and Director™ Liquid Handler, integrated with the Nova Biomedical BioProfile® FLEX2 Analyzer, provide a fully automated solution for real-time bioprocess sampling, analysis, data management, and process control.
For more information on the Nova Biomedical BioProfile FLEX2 integration, please visit their website.
Related Products: Director™
Description
System Configuration and Capacity
The Seg-Flow® PS and Director™ combination provides automated sampling from up to 16 bioreactors and delivers samples to the BioProfile FLEX2 or other connected analytical instruments. Unlike many automated sampling systems, the Seg-Flow connects directly to the FLEX2 application programming interface (API), providing a more stable and reliable connection between the sampling system and the analyzer. The system can also be configured to route samples to as many as four analyzers, allowing multiple critical process parameters to be measured through a single automated sampling platform.
For smaller configurations, the Seg-Flow PS can connect up to two bioreactors directly to the BioProfile FLEX2 without requiring a Director. When more than two bioreactors are connected, the Director manages sample routing and coordination between the vessels and the analyzer.
Product Specifications
| Software Integration | Native integration with the Nova Biomedical BioProfile FLEX2 using the FLEX2 Application Programming Interface (API) |
|---|---|
| Communication | Bidirectional communication between the Seg-Flow® software and the BioProfile FLEX2 |
| Fluid Connection | Connection to the sample port located on the right side of the BioProfile FLEX2 |
| Required FLEX2 Hardware | The FLEX2 EOLS Automation Kit from Nova Biomedical must be installed before the Seg-Flow can be integrated |
Features & Benefits
- Fully automated bioprocess sampling and analysis — Integrates the Seg-Flow® PS Fully Automated Sampling System and Director™ Liquid Handler with the Nova Biomedical BioProfile® FLEX2 Analyzer.
- Bioreactor Capacity — Supports automated sampling from 1 to 16 bioreactors. The Seg-Flow® PS can connect directly to the BioProfile FLEX2 for applications with up to two bioreactors. The Director™ Liquid Handler is required for systems with more than two bioreactors.
- Compatible Bioreactor Sizes — Compatible with bioreactors ranging from 100 mL laboratory-scale vessels to 2,000 L production-scale bioreactors.
- Software Integration — Native integration with the Nova Biomedical BioProfile FLEX2 using the FLEX2 Application Programming Interface (API) for bidirectional communication.
- Supports multiple analytical devices — Delivers samples to the BioProfile FLEX2 and up to three analytical devices through a single automated sampling platform.
- Built-in fraction collection — The Director automatically collects, cools, and retains samples for offline testing, confirmatory analysis, or future evaluation.
- Cell-containing and cell-free sampling — Supports a wide range of batch, fed-batch, continuous and perfusion process applications.
- Customizable sampling schedules — Set individual sampling frequencies for each bioreactor based on specific process and analytical requirements.
- Automated data acquisition — BioProfile FLEX2 results are automatically collected and associated with the correct bioreactor and sampling event.
- Real-time process monitoring — Provides frequent measurements of cell density, viability, nutrients, metabolites, gases, and other critical bioprocess parameters.
- Automated feed-control capabilities — Uses real-time nutrient and metabolite measurements to support automated feed-control strategies.
- OPC UA connectivity — Transfers BioProfile FLEX2 results and Seg-Flow process data to compatible SCADA systems, distributed control systems, historians, and bioprocess management platforms.
- Reduced manual sampling — Minimizes operator involvement, improves sampling consistency, and reduces the time required for routine sample collection and analysis.
- Enhanced process understanding and control — More frequent analytical data supports improved process monitoring, faster decision-making, and greater bioprocess control.
Literature
FLEX2 Seg-Flow Integration
Flownamics® has been creating innovative, high quality solutions for the biotechnology and bioprocess industry for over 30 years.
Our products provide our users with the tools that they need to improve their processes through automation. This results in higher quality data, more time, and a better work/life balance by requiring less off shift and weekend workloads. Contact Flownamics® to see how our products can make a difference for your process.
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