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Seg-Flow S3

Smart flow control
Improved ease of use
Optimized operator interface
Increased reliability
LED status lights

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Seg-Flow 1200

Single-use fluid path
Sampling for 1-2 reactors
10” W x 7” H x 10” D
(25.4 cm x 17.8 cm x 25.0 cm)

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Seg-Flow 4800

Single-use fluid path
Sampling for up to 8 reactors
11”W x 10 ¼”H x 14”D
(27.9 cm x 26.0 cm x 35.6 cm)

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Seg-Flow 8000i

Chemically inert fluid path
Sampling for up to 8 reactors
11”W x 10 ¼”H x 14”D
(27.9 cm x 26.0 cm x 35.6 cm)

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Automated On-Line Sampling Solutions

The Seg-Flow® Automated On-line Sampling System provides multiple bioprocess monitoring and control solutions for improving process performance. The Seg-Flow system’s patented Segmented On-line Sampling™ technology allows rapid and accurate sampling for 8 vessels or process streams and sample delivery to 4 analyzers and/or fraction collectors. Several feed control options are available with the Seg-Flow system, which can control 2 pumps per vessel. Existing off-line and at-line analytics are seamlessly integrated into a multi-functional on-line PAT tool through the Seg-Flow system’s communication interface and FlowWeb™ control software. The FlowWeb software simultaneously acquires all integrated instrument data and can export the data to any OPC-enabled SCADA for enhanced process monitoring and control.

Sampling Solutions

• Rapid and accurate sampling
• Sample from 1-8 vessels/process streams
• Deliver samples to 4 analyzers/fraction collectors
• Withdraw cell-free or cell-containing samples
• On-line monitoring of nutrients, metabolites and cell growth
• Sample line is cleaned and/or sterilized after every sample

Instrument Integrations

• Beckman-Coulter Vi-CELL® XR Cell Analyzer
• Kaiser RamanRxn2™ Multi-Channel Analyzer
• Mettler-Toledo Balances
• Nova® Biomedical BioProfile® FLEX 2, FLEX, Basic, 100, 300, and 400 analyzers
• Roche Cedex Bio HT
• Roche Cedex HiRes Cell Analyzer
• YSI® 2700, 2900, 2950, and 7100 Biochemistry Analyzers

Feed Control Options

• Control 2 feed pumps per vessel
• Setpoint control, gravimetric feed control
• Other feed algorithms can be programmed
• Pump interfaces include: Watson-Marlow, Cole-Parmer®,
  MasterFlex®, SciLog® ACCU Digital, and Ivek
• Other pump interfaces available upon request

SCADA Integrations

• Sartorius BioPAT® MFCS
• Eppendorf BioCommand®
• Broadley-James BioNet®
• Emerson Delta V
• Other devices and SCADA available upon request

Communication Interfaces

• Serial – RS-232
• Analog I/O