The Seg-Flow® Automated On-line Sampling System provides multiple bioprocess monitoring and control solutions for improving process performance. The Seg-Flow® system’s patented Segmented On-line Sampling technology allows rapid and accurate sampling for 8 vessels or process streams and sample delivery to 4 analyzers and/or fraction collectors. Several feed control options are available with the Seg-Flow® system, which can control 2 pumps per vessel. Existing off-line and at-line analytics are seamlessly integrated into a multi-functional on-line PAT tool through the Seg-Flow® system’s communication interface and FlowWeb™ control software. The FlowWeb™ software simultaneously acquires all integrated instrument data and can export the data to any OPC-enabled SCADA for enhanced process monitoring and control.
The new generation of the Flownamics® automated sampling system, the Seg-Flow S3® product line, is characterized by robust hardware, the intuitive handling of hoses with intelligent pinch valves and non-contact ultrasonic sensors. A series of LED status lights indicate the phases of sampling and the sequence of cleaning, rinsing, sampling, air, idling and the end of the process.
The new user interface offers intuitive menus with more planning options and reagent status information. The optional Sample-Mod S3® module is used for sample pre-dilution in selectable steps up to 1:10, can automatically add reagents to the native sample and distributes the sample to up to four analysis or filling systems. The cleaning and disinfection of the flow channel takes place from the central Reagent-Mod S3®module. The cooled filling station models FlowFraction 400 fill the sample into sample vessels, e.g. 15 ml centrifuge tubes.